We seem to be having this problem in Enscape 3.3.1 inside Rhino7 SR14. When launching Enscape from a 3D viewport, we do not have the option to edit any Visual Settings, the button is grayed out, along with several other buttons.
We did find that it seems to be specific to the file we're in. Other files we open, do not have the same problem when launching Enscape. We've gone as far as to copy/paste the entire building's content into a new blank file. This works for a while but, when coming back to that new file the next day the problem persists.