Did you try to launch Enscape with that model and see what happens?
The biggest VRAM consumers are textures and Enscape itself (frame buffer, acceleration structures, shadow maps and so on). Geometry usually does not take much space. Views, sheets, etc. do not have any significant effect on the Enscape memory consumption at all.
To use as little memory as possible for Enscape itself, you should try to switch to "Draft" quality mode prior to starting Enscape with that model. Also keep Enscape window small - if you have a 4k display and have Enscape fullscreen - you have lost a few gigabytes of VRAM already.
Textures are scaled down with respect to the world size they occupy, where possible. Even if you have hundreds of textures in the project it will be somewhat hard to waste more that 1-2 gigabytes for textures.
What will really be bad is startup time. Exporting and processing all the geometry and scaling textures may take much time. But you still could try and see what will happen.